Cell fate and patterning
Biology of centrosomes and genetic instability
Institut Curie
Our laboratory aims to uncover the principles that govern cell proliferation during development and to determine how genetic instability contributes to the early stages of disease.
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Cell Biology of Mammalian Neurogenesis
Institut Curie
Our group focuses on the mechanisms governing neocortex development, with a strong interest on the role and regulation of the neural stem cells.
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Cell division and neurogenesis
IBENS
Our goal is to understand how neural stem cells choose between proliferation and differentiation during development of the nervous system.
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Cell fate, plasticity and reprogramming
Institut Cochin
Our lab seeks to uncover and comprehend gene regulatory networks and chromatin rearrangements regulating the reemergence of pluripotency programs and the underlying reprograming of cellular identity during development and regeneration.
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Cilia biology and neurogenesis
IBENS
Our
projects focus on understanding how brain multiciliated cells –called ependymal
cells– develop. Their unique location, morphology and function strongly suggest
that they actively contribute to the formation and maintenance of neural
circuits.
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Comparative Developmental Neurobiology
Institut Jacques Monod
We study
how neuronal diversity evolves and how developmental programs generate this
diversity. By focusing on the insect visual brain, we aim to uncover general
principles linking development, evolution, and neural circuit organization.
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Development and Evolution of the Forebrain
NeuroPSI
We seek to understand the developmental mechanisms and
principles underlying the evolution of brain and behaviors in vertebrates.
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Morphogens and Neural Development
NeuroSU
We investigate how morphogens, which are extracellular secreted molecules, precisely guide the distinct steps of neuronal development—including generation, differentiation, migration, and connectivity.
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Brain Development (BrainDev)
Brain Paris Institute
Our team is studying the transcriptional control of embryonic neural stem cells, as well as the emergence of visual circuits and neural networks responsible for behaviour and the transcriptional control of embryonic stem cells.
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Neurogenesis and circuit development
Institut de la Vision
We study how the cells that constitute brain and retinal circuits are generated, differentiate and interconnect during development.
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Neural network and axonal development
Brain Development and Plasticity
IBENS
Our general goal is to understand how functional forebrain circuits, which enable sensory perception, motor responses and cognition, wired up during development.
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Development and function of the vertebrate visual system
Institut de la Vision
Our laboratory investigates the molecular determinants that control the
proper development of the axonal connections between the eye and the visual
brain.
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Development, evolution and function on commissural systems
Institut de la Vision
Our team tries to understand how axonal guidance molecules regulate cellular interactions during the development of the visual system and in ocular diseases.
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Genetics and development of the cerebral cortex
Institut Imagine / IPNP
Our team investigates the molecular mechanisms of cerebral cortex development, and how their alteration can lead to neurodevelopmental disorders.
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Interactions between neurons and oligodendroglia in myelination and myelin repair
IPNP
Our team is interested in understanding the roles of neuron-oligodendroglia interactions during postnatal cortical development and in pathological conditions.
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Mechanics of neuronal development
Dev2A
Our lab investigates how neural tissues acquire their
shape and function during development (morphogenesis), and how neuronal
circuits assemble in the embryo (neuronal circuit formation)
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Mechanisms of sensory map development
Institut de la Vision
We study the local and temporal coding of cellular signals and signalling molecules regulating the development of neuronal networks and sensory maps with particular interest in the connection between the retina and the brain.
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Molecular Control of Neuro-Vascular Development
CIRB
Our laboratory studies vascular and neuronal development, with particular interests in mechanisms that direct patterning and guidance. Our research is focused on the relationship between vascular and nervous system and how they develop interactions at a molecular level.
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Molecular Identity and DIversity of SYNapses in the Brain (MIDISYN)
CIRB
Our team's aim is to identify the molecular determinants of synapse diversity, how they are modulated by the early life environment and understand how these determinants contribute to normal network formation and function in the mammalian brain.
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mRNA transport in neurons
NeuroSU
We explore the cellular and molecular mechanisms involved in the transport of mRNAs in neurons.
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Neuroimmunity, development and plasticity
NeuroSU
We study how mechanisms of immunity, in particular microglial cells, the brain resident immune cells, shape the construction of brain circuits. We seek to understand how dysregulation of neuro-immune interactions favors the emergence of neurodevelopmental and psychiatric disorders, or impairs brain plasticity.
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Neurodevelopmental disorders
Brain Development and dysfunction in neurogenetic diseases (NeuroGen)
Paris Brain Institute
Our team focus on neurogenetic diseases, spinocerebellar degenerations – SCD (spastic paraplegias and cerebellar ataxias), frontotemporal lobar degenerations – FTLD and Huntington disease.
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Brain Development and Epilepsy
Institut Imagine
Our laboratory combines expertise in developmental neuroscience (DJ) and pediatric neurosurgical research and practice (TB). Our goal is to understand the mechanisms of developmental epilepsies to develop innovative therapies.
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Clinical and experimental epilepsy (EpiC)
Paris Brain Institute
Our team explores how the brain becomes epileptic, how it produces
seizures and the relationships between neurophysiological activities and
clinical semiology.
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Cortical Development & Microcephaly
NeuroDiderot
Our group is interested in cortical development and, in particular, developmental abnormalities that lead to human microcephaly.
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Cortical Development and Pathology
NeuroSU
Our team investigates the molecular and cellular mechanisms of neocortical and hippocampal development, with a focus on cortical malformations and neurodevelopmental disorders.
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Developmental Brain Disorders
Institut Imagine
Our project
aims to decipher the molecular defects underlying cognitive disorders and to
elucidate the pathophysiological mechanisms leading to cognitive impairment.
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Genetic Mosaicism in Epilepsy and Neurodevelopmental Disorders (MOSAIC)
Paris Brain Institute
Our laboratory is dedicated to elucidating the precise mechanisms by which brain somatic mutations contribute to epileptogenesis in the context of cortical malformations.
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Human neurodevelopment and disorders
Institut Jacques Monod
Our team investigates the cellular and molecular mechanisms underlying human development and disease, including rhabdomyosarcoma, neural tube defects, spinal muscular atrophy (SMA), and amyotrophic lateral sclerosis (ALS).
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Stem Cells and Neurogenesis in the Retina (SCaNR)
NeuroPSI
We seek to understand the mechanisms underlying the development, survival and regeneration of retinal cells, with the objective of therapeutic strategies, including neuroprotection, gene therapy and cell therapy.
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Somatic mosaicism in neurodevelopment and disease
Institut Imagine
Our lab studies somatic mosaicism with the double objective of 1) understanding normal and pathological neurodevelopment and 2) exploring the role of somatic mosaicism in neurodevelopmental disorders.
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Physiology and Physiopathology of the Gliovascular Unit
CIRB
Our ambition is to provide essential knowledge on the mechanisms underlying astroglial control of cerebrovascular functions in health and disease.
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